PROJECTS
Standardized Bilirubin Phototherapy System (SBPS)
Background of Project
Phototherapy is a widely recognized and effective treatment for physiological jaundice, a common condition affecting approximately 60% of newborns and preterm infants each year in the United States. Jaundice, characterized by a yellow discoloration of the skin due to elevated levels of unconjugated bilirubin, requires prompt treatment. If left untreated, it can lead to hyperbilirubinemia, which may result in serious neurological complications.
Traditionally, phototherapy for reducing bilirubin levels in jaundiced infants operates within a spectral range of 400 nm to 520 nm, with peak effectiveness around 450 nm. However, the absence of universal standardization among manufacturers has led to inconsistencies in light measurement, causing challenges in achieving consistent treatment protocols.
Pediatric associations in the United States recommend an irradiance intensity of 30 µW/cm²/nm for optimal jaundice treatment. However, variations in light sources and mismatches with radiometers used to measure irradiance have hindered the reliable delivery of this standard in clinical settings.
Recent research indicates that the most effective treatment falls within the 470 nm to 490 nm spectrum, centered at 475 nm. This specific range has shown to provide optimal phototherapy outcomes for newborns with jaundice.
Normalized Spectra of Other Light Source Spectrum and Radiometer response
Normalized Spectra of Our LED Spectrum and Radiometer response
Solution
​Our solution offers key features:
-
Microprocessor-Controlled LED Light Source
Operating at 475 nm ± 10 nm with a direct irradiance reading display. -
Variable Light Power Control
Adjustable up to a peak of 100 µW/cm²/nm. -
Matching Radiometer for Self-Calibration
The system includes an accessory radiometer designed for the monthly self-calibration of the SBPS by clinical technicians. This radiometer functions as a transfer standard and should be forwarded annually to a metrology lab for NIST traceable calibration to ensure ongoing accuracy and reliability. -
Data Management
Software integration for efficient data collection and analysis, providing valuable insights for clinicians, epidemiologists and researchers.
​
Additionally, our prototype SBPS incorporates a microcontroller with a touch-screen display for precise control and monitoring of phototherapy dosage. accessory radiometer is provided and precalibrated by a metrology laboratory that serves as a transfer standard for self-calibration SBPS, accesory radiometer should be forwarded annually to a metrology lab for NIST traceable calibration to ensure ongoing accuracy and reliability.​​
​
Our Standardized Bilirubin Phototherapy System (SBPS) features a modular and versatile design, making it adaptable for the treatment of various dermatological conditions such as acne, psoriasis, atopic dermatitis, and eczema. By adjusting the light wavelength spectrum to target specific conditions, this innovative product offers a flexible solution that can be customized for optimal therapeutic outcomes across different skin disorders.
​
We invite investors and partners who share our vision of transforming healthcare to join us in commercializing this groundbreaking product.
​
Contact us today to learn more about our innovative solution and explore partnership opportunities. Let's work together to bring this cutting-edge technology to the market and improve the lives of countless individuals in need of effective and reliable phototherapy treatments.